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中国临床研究:2019,32(3):313-316
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胸痛中心建立对急性ST段抬高型心肌梗死患者行急诊PCI相关指标与住院预后的影响
(南通大学附属南京江北人民医院胸痛中心,江苏 南京 210048)
Impacts of chest pain center establishment on emergency PCI related indicators and in-hospital outcomes in patients with acute ST-segment elevation myocardial infarction
(Chest Pain Center of Nanjing Jiangbei People′s Hospital Affiliated to Nantong University, Nanjing, Jiangsu 210048, China)
摘要
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投稿时间:2018-08-19   网络发布日期:2019-03-20
中文摘要: 目的 观察胸痛中心建立对急性ST段抬高型心肌梗死(STEMI)患者急诊经皮冠状动脉介入治疗(PCI)相关指标:进门-球囊扩张时间(D2B)、D2B达标率、采血到肌钙蛋白报告时间、首次医疗接触(FMC)到首份心电图时间的影响,以及对住院预后的影响。方法 选择胸痛中心成立前、后9个月的104例STEMI患者作为研究对象,分为胸痛中心成立前组(绿色通道组,n=45)和胸痛中心成立后组(胸痛中心组,n=59),比较两组的D2B时间、PCI次日心力衰竭发生率、住院病死率等指标。结果 胸痛中心成立后D2B时间较成立前明显下降[(90.5±39.0)min vs (148.9±67.9)min,P<0.01],达标率提高(59.3% vs 22.2%,P<0.01);胸痛中心成立后的PCI次日心力衰竭发生率较成立前稍下降(11.9% vs 15.6%,P<0.05),住院病死率稍高(8.5% vs 0,P>0.05),但差异无统计学意义;胸痛中心成立后采血到肌钙蛋白报告时间、FMC到首份心电图时间逐月下降并达胸痛中心认证标准。结论 胸痛中心建立后,对STEMI患者行急诊PCI,可明显缩短D2B时间,提高D2B达标率,有利于改善STEMI患者心功能。
Abstract:Objective To observe the impacts of the establishment of chest pain center (CPC) on emergency percutaneous coronary intervention (PCI) related indicators including door to balloon (D2B) time, D2B standard-reaching rate, time from taking blood to troponin report, time from first medical contact (FMC) to the first ECG record and in-hospital outcomes in patients with acute ST-elevation myocardial infarction (STEMI) undergoing primary PCI. Methods A total of 104 STEMI patients 9 months before and after CPC establishment were selected as research objects. The patients were divided into the group before CPC establishment (green channel group, n=45) and group after CPC establishment (CPC group, n=59). The D2B time, incidence of heart failure on the next day of PCI and in-hospital mortality were compared between two groups. Results Compared with pre-establishment of CPC, D2B time decreased significantly [(90.5±39.0) min vs (148.9±67.9) min, P<0.01], and D2B standard-reaching rate increased significantly (59.3% vs 22.2%, P<0.01) after CPC establishment.Compared with pre-establishment of CPC, the incidence of heart failure on the next day of PCI decreased slightly (11.9% vs 16.0%, P>0.05) , and in-hospital mortality increased slightly (8.5% vs 0, P>0.05) after CPC establishment. The time from taking blood to troponin report and the time from FMC to the first ECG record monthly declined and reached the CPC certification standard after CPC establishment. Conclusion CPC establishment can obviously shorten D2B time, raise D2B standard-reaching rate and improve cardiac function for STEMI undergoing emergency PCI.
文章编号:     中图分类号:    文献标志码:A
基金项目:南京江北人民医院院级科研(JKK201705)
引用文本:
尹克金,曹正雨,张小兵,夏思良.胸痛中心建立对急性ST段抬高型心肌梗死患者行急诊PCI相关指标与住院预后的影响[J].中国临床研究,2019,32(3):313-316.

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