Abstract:Objective To investigate the correlation between thyroid function and renal function by way of the detection of thyroid hormone levels and renal function in patients with different thyroid function status. Methods From January 2015 to May 2017, 60 patients with hyperthyroidism (hyperthyroidism group), 62 patients with hypothyroidism (hypothyroidism group) and 59 healthy people (control group) were selected from people received medical treatment or physical examination. The thyroid function and renal function were detected and estimated glomerular filtration rate (eGFR) was calculated in two groups. Results Compared with control group, eGFR was higher in hyperthyroidism group and it was lower in hypothyroidism group (P<0. 01). There was a significant negative correlation between eGFR and thyroid-stimulating hormone (TSH) (P<0. 01), and a significant positive correlation with free triiodothyronine (FT₃) (P< 0.01), but no significant correlation with FT₄ (P>0. 05). Conclusion Thyroid function could be closely related to the renal function. The abnormal thyroid hormone level could significantly affect the renal function of the patients. It is of certain clinical significance to monitor the renal function of patients with abnormal thyroid function.