Abstract:Objective To investigate the influence of laparoscopic choledocholithotomy on operation time, peristalsis recovery and recurrence rate in patients with gallstone. Methods A total of 108 patients with gallstone who received treatment from June 2015 to November 2016 were selected and divided into control group and observation group according to random number table (n=54, each). Control group patients received laparoscopic cholecystectomy and observation group patients received laparoscopic choledocholithotomy. The operation time, time of peristalsis recovery and recurrence rate were compared between two groups. Results Compared with control group, observation group had shorter incision length [(1.06±0.17)cm vs (2.55±0.42)cm], fewer intra-operative bleeding [(8.72±1.36)ml vs (14.35±2.28)ml], shorter hospital stay [(3.64±0.53)d vs (4.78±0.76)d] and longer operation time[(41.82±6.85)min vs (33.57±5.49)min] (all P<0.01). The peristalsis recovery time [(30.65±5.12)h vs (35.28±5.74)h], bowel sound recovery time [(10.65±1.74)h vs (14.37±2.36)h], first exhaust time [(18.25±3.13)h vs (23.86±4.09)h], first defecations time[(21.42±3.56)h vs (24.78±4.13)h] were shorter, visual analogue scale was lower and the score of short form (36) health survey was higher significantly in observation group (all P<0.01). There were no significant difference in complication rate and gallstone recurrence rate between two groups (all P>0.05). Conclusion In the treatment of gallstone, laparoscopic choledocholithotomy could significantly improve operation related symptoms and promote intestinal recovery with a good safety.