Abstract:Objective To investigate the short- and long-term prognosis of combined therapy based on tension-reduced suture for chest keloids. Methods A total of 90 patients with chest keloids who were treated from February 2012 to June 2017 were selected and divided into study group and control group randomly (45 cases each). The study group patients were treated with tension-reduced suture and silicone gel for external use for 8 months after the radiation therapy. The control group was treated with traditional suture and postoperative radiotherapy. Results All the patients healed well and the incisions healed at first grade without serious complication. The total effective rate in study group was significant higher than that in control group at 1 month after the operation (97.8% vs 86.7%, P<0.05). The keloid hardness in study group was lower than that in control group at 8 months after the treatment [(0.62±0.22) N/mm³ vs (0.70±0.14) N/mm³, P<0.05], and both of them was lower than that before the treatment [(0.62±0.22) N/mm³ vs (0.77±0.22) N/mm³, (0.70±0.14) N/mm³ vs (0.78±0.21) N/mm³, all P<0.05]. Patient and observer scar assessment scoring (POSAS) in both group was decreased after the treatment, and the POSAS in study group was lower than that in control group after the treatment (all P<0.05). Conclusion short- and long-term prognosis of combined therapy based on tension-reduced suture is safe and effective in the treatment of chest keloid. It can improve the therapeutic effect in the near future, and it also can reduce the hardness of scar and improve the condition of scar in the long term.