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投稿时间：2017-10-23 网络发布日期：2018-03-20
投稿时间：2017-10-23 网络发布日期：2018-03-20
中文摘要: 目的 分析中国人Cronkhite-Canada综合征(CCS)的临床特点。方法 在PubMed和中国文献数据库中检索1985年1月至2017年1月文献中报道的患有CCS的中国人,并对其临床资料进行回顾性分析。结果 82例中国人患者中,以胃肠道弥漫性多发息肉及至少一项外胚层改变为主要临床特点。临床上对于该病的诊治主要依靠临床经验,故而该病的治疗方案多种多样的,包括糖皮质激素、抗生素、抑酸药物、抗幽门螺杆菌、对症及营养支持、内镜下治疗、外科治疗和中医治疗等。结论 CCS发病率在我国很低,该病的诊断依赖于患者的临床症状及胃肠镜和病理学检查,但是目前国内外尚无特效的治疗方案。
中文关键词: Cronkhite-Canada综合征 胃肠道多发息肉 外胚层改变 糖皮质激素
Abstract:Objective To investigate the clinical features of Cronkhite-Canada syndrome(CCS).? Methods Relevant data of Chinese CCS patients from 1985 to 2017 retrieved from PubMed and Chinese biomedical database was retrospectively analyzed.? Results All the 82 Chinese CCS patients had been reported with the clinical characteristics of gastrointestinal polyposis with at least one ectodermal change. The diagnosis and treatment of this disease mainly depend on clinical experience. Therefore, there were various treatments for this disease, including corticosteroids, antibiotics, anti acid drugs, anti Helicobacter pylori, symptomatic and nutritional support, endoscopic treatment, surgical treatment and traditional Chinese medicine treatment.? Conclusion Incidence of CCS is low in our country, and diagnosis depends on clinical characteristics, digestive endoscopy and pathology findings. However, there is no optimal treatment for CCS at home and abroad.
keywords: Cronkhite-Canada syndrome Diffuse gastrointestinal polyposis Ectodermal changes Glucocorticoid
文章编号： 中图分类号：R 57 文献标志码：B
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引用文本：
晁帅恒，李修岭，张梦婷，黄宇博，吴贝贝，高鹤云，刘文丽.Cronkhite-Canada综合征83例临床分析[J].中国临床研究,2018,31(3):397-399.
晁帅恒，李修岭，张梦婷，黄宇博，吴贝贝，高鹤云，刘文丽.Cronkhite-Canada综合征83例临床分析[J].中国临床研究,2018,31(3):397-399.