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投稿时间：2020-12-25 网络发布日期：2021-09-20
投稿时间：2020-12-25 网络发布日期：2021-09-20
中文摘要: 目的 回顾性分析隔离病房新型冠状病毒感染疑似患者116例的流行病学、临床特征、治疗和转归，为防控新型冠状病毒感染提供参考。方法 选取2020年1月26日至6月30日南京江北医院隔离病房收治的116例新型冠状病毒感染疑似患者作为研究对象，收集患者的人口学资料、流行病学资料、基础疾病、临床表现、实验室资料、胸部CT影像资料、治疗及预后资料，进行回顾性分析。结果 116例新型冠状病毒感染疑似患者，男性70例（60.3％），女性46例（39.7％），中位年龄46.1（30,62）岁;南京市91例（78.4％），湖北省患者5例（4.3％）;18～59岁以下患者85例（73.3％）;合并有基础疾病患者27例（23.3％）。确诊新型冠状病毒肺炎（普通型）1例，排除新型冠状病毒感染115例。发热和咳嗽是常见临床症状。接受机械通气治疗的患者中外周血淋巴细胞减少、凝血功能障碍、肝肾功能损害较其他患者常见，磨玻璃影和实变是疑似感染患者胸部CT早期常见改变。呼吸支持治疗4例，升白细胞治疗3例，保肝治疗14例。结论 新型冠状病毒感染疑似病例临床表现无特异性，容易与多种疾病混淆，应密切关注病情进展，结合新型冠状病毒核酸检查结果，及时研判病情变化，尽早明确诊断，调整治疗方案，努力提高相关疾病救治成功率。
中文关键词: 新型冠状病毒感染疑似患者 流行病学 临床特征 胸部CT 预后
Abstract:Objective To retrospectively analyze the epidemiology, clinical characteristics, treatment and outcome of 116 suspected cases of COVID-19 in isolation wards, so as to provide reference for prevention and control of COVID-19. Methods A total of 116 patients with suspected COVID-19 who were admitted to the isolation ward of Nanjing Jiangbei Hospital from January 26 to June 30, 2020 were selected as the research object. The demographic data, epidemiological data, basic diseases, clinical manifestations, laboratory data, chest CT images, treatment and prognosis of patients were collected and retrospectively analyzed. Results Among the 116 suspected cases of COVID-19, there were 70 cases of males (60.3%) and 46 cases of females (39.7%). The age of the patients ranged from 18 to 88 years, with a median age of 46.1 years old, and there were 85 patients (73.9%) under 59 years old. There were 91 patients from Nanjing (78.4%) and 5 patients (4.0%) from Hubei, and 27 patients (23.3%) with basic diseases. One case was diagnosed with COVID-19 (general type), and 115 cases were excluded from COVID-19. Fever and cough were common clinical symptoms. Peripheral blood lymphocytopenia, coagulation dysfunction and liver and kidney function damage in patients treated with mechanical ventilation were more common than other patients. Ground glass shadow and consolidation were common early changes of chest CT in patients with suspected COVID-19. There were 4 cases of respiratory support treatment, 3 cases of leukocyte raising treatment and 14 cases of liver protection treatment. Conclusion The clinical manifestations of suspected cases of COVID-19 are not specific, and are easy to be confused with a variety of diseases. The progress of the disease should be paid for close attention. Combined with the results of COVID-19 nucleic acid examination, the changes of the disease should be judged, the diagnosis should be made, and the treatment plan should be adjusted as soon as possible, in order to improve the success rate of the treatment of the related diseases.
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基金项目:
| 作者 | 单位 |
| 杨震1 | 1. 南通大学附属南京江北医院呼吸内科，江苏 南京 210048 |
| 彭程2 | 2. 南通大学附属南京江北医院感染内科，江苏 南京 210048 |
| 卜顺林3 | 3. 南通大学附属南京江北医院影像科，江苏 南京 210048 |
| Author Name | Affiliation |
| YANG Zhen*, PENG Cheng, BU Shun-lin | Department of Respiratory Medicine, Nanjing Jiangbei Hospital Affiliated to Nantong University, Nanjing, Jiangsu 210048, China |
引用文本：
杨震,彭程,卜顺林.新型冠状病毒感染疑似患者116例临床分析[J].中国临床研究,2021,34(9):1175-1180.
杨震,彭程,卜顺林.新型冠状病毒感染疑似患者116例临床分析[J].中国临床研究,2021,34(9):1175-1180.