本文已被：浏览 470次 下载 271次
投稿时间：2020-05-15 网络发布日期：2020-11-20
投稿时间：2020-05-15 网络发布日期：2020-11-20
中文摘要: 目的 分析血液交叉配合试验不相合原因,为临床精准输血提供依据。方法 对2014年1月至2019年6月南京江北人民医院交叉配血不合标本97例,采用盐水法、微柱凝胶法、抗人球蛋白法进行输血相容性检测、不规则抗体筛查抗体特异性鉴定。结果 97例交叉配血不合标本中,主侧不合73例(75.26%),次侧不合24例(24.74%);受血者因素引起的87例(89.69%),供血者因素引起的10例(10.31%);其中87例配血不合受血者标本中,Rh血型系统占47.13%,温自身抗体占26.44%,冷自身抗体占10.34%,其他血型系统占12.64%,ABO亚型为3.45%。结论 Rh血型系统产生的不规则抗体和温自身抗体是引起交叉配血不相合的主要原因,发现存在同种抗体时,应选择对应抗原阴性的红细胞进行同型输注。
Abstract:Objective To analyze the incompatibility cases in cross matching blood test to provide evidence for precise blood transfusion.Methods From January 2014 to June 2019 in Nanjing Jiangbei People′s Hospital,97 samples of cross-matching incompatibility were tested for blood transfusion compatibility,irregular antibody screening and antibody specificity identification by method of purifying brine,microcolumn gel test and anti-human globulin test.Results In 97 samples of crossmatch incompatibility,73 cases (75.26%) were mismatched between the main sides and 24 cases (24.74%) between the second sides;87 cases (89.69%) were caused by recipient factors,and 10 cases (10.31%) were from donor factors.In 87 incompatible recipients,Rh blood group system accounted for 47.13%,warm autoantibodies accounted for 26.44%,cold autoantibodies accounted for 10.34%,other blood group system accounted for 12.64% and ABO blood group subtype was 3.45%.Conclusions Irregular antibodies and warm autoantibodies produced by Rh blood group system are the main causes of mismatching.In the presence of alloantibodies,the corresponding red blood cells with antigen negative should be selected for homotypic transfusion.
文章编号： 中图分类号： 文献标志码：B
基金项目:
| Author Name | Affiliation |
| SUN Hong,GUO Yang,WANG Min | Department of Blood Transfusion,Nanjing Jiangbei People′s Hospital of Nantong University,Nanjing,Jiangsu 210048,China |
引用文本：
孙鸿, 郭阳, 王敏.97例血液交叉配合试验不合原因分析[J].中国临床研究,2020,33(11):1530-1532,1536.
孙鸿, 郭阳, 王敏.97例血液交叉配合试验不合原因分析[J].中国临床研究,2020,33(11):1530-1532,1536.