Abstract:Objective To investigate the application effect and advantage of modified jailed balloon technique (modified-JBT) in percutaneous coronary intervention (PCI) of coronary bifurcation lesion compared with standard JBT. Methods A total of 82 patients with true coronary bifurcation lesion who received PCI from February 2017 to January 2019 were selected and divided into modified group and standard group randomly (n=41,each).The modified group received modified JBT to protect the side branch(SB),and the standard group received standard JBT.The cardiac complications of intraoperation and 6 months after the operation,PCI success rate,TIMI grade of main vessel (MV) and SB,SB obstruction,angina pectoris and the related indexes of interventional therapy were compared between the two groups.Quantitative coronary angiography (QCA) software was used to analyze the patency of SB at MV pre-expansion,immediately after PCI and 6 months after PCI. Results Compared with standard group,the operation time of PCI was significantly shorter,the amount of received radiation was significantly less,and the number of used balloons and the cost of operation were significantly more in modified group (P<0.05,P<0.01).There was no significant difference in the number of used guide wires and the amount of contrast agent between the two groups (P>0.05).No significant difference occurred between modified group and standard group in TIMI blood flow rate of SB after MV balloon pre-expansion (78.05% vs 68.29%,P>0.05).The grade 3 rate of SB blood flow was higher immediately after PCI than that after pre-expansion in two groups,and it was significantly higher in modified group than that in the standard group (95.12% vs 80.49%,P=0.043).Six months after the operation,the SB blood flow rate of the modified group was slightly higher than that of the standard group without significant difference (100.00% vs 87.80%,P>0.05).There was no significant difference in complication rate between the two groups (P>0.05). ConclusionModified JBT is helpful to improve the SB patency rate in coronary bifurcation lesion,reduce PCI operation time and radiation exposure,but the operation cost is slightly increased.