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投稿时间：2019-05-30 网络发布日期：2020-02-20
投稿时间：2019-05-30 网络发布日期：2020-02-20
中文摘要: 目的 探讨消癥杀胚方治疗输卵管妊娠气滞血瘀证的临床疗效。方法 将2017年7月至2018年11月于河北燕达医院就诊的88例输卵管妊娠患者随机分为观察组和对照组,各44例。对照组采用米非司酮治疗。观察组在对照组基础上,采用消癥杀胚方治疗。两组均治疗14 d。对比两组的疗效,腹痛消失时间、包块消失时间、血人绒毛膜促性腺激素(HCG)恢复正常时间、月经恢复时间,治疗前后血清雌二醇、孕酮、HCG的水平。记录患者治疗过程中不良反应的发生情况。结果观察组总有效率高于对照组,差异有统计学意义(93.18% vs 77.27%,P<0.05)。治疗后，两组雌二醇、孕酮、HCG水平显著低于治疗前，且观察组低于对照组,差异有统计学意义(P<0.01)。观察组腹痛消失时间、包块消失时间、血HCG恢复正常时间、月经恢复时间短于对照组,差异有统计学意义(P<0.01)。两组的不良反应总发生率差异无统计学意义(13.64% vs 18.18%,P>0.05)。结论消癥杀胚方联合米非司酮治疗输卵管妊娠的临床疗效较好,可改善患者的临床症状。
Abstract:Objective To investigate the clinical effect of Xiaozheng Shapei decoction in the treatment of tubal pregnancy with syndrome of Qi stagnation and blood stasis.Methods A total of 88 patients with tubal pregnancy who received treatment at Hebei Yanda Hospital from July 2017 to November 2018 were selected and divided into observation group and control group randomly (n=44,each).The control group was treated with mifepristone.On the basis of the control group,the observation group was treated with Xiaozheng Shapei decoction.Both groups were treated for 14 days.The clinical effect the disappearance time of abdominal pain,the disappearance time of mass,the recovery time of human chorionic gonadotropin (HCG),the recovery time of menstruation,the levels of serum estradiol,progesterone and HCG were compared between two groups.The adverse reactions were recorded during the treatment.Results The total effective rate of the observation group was significantly higher than that of the control group (93.18% vs 77.27%,P<0.05).After treatment,the levels of estradiol,progesterone and HCG in the two groups were significantly lower than those before treatment (P<0.01).After the treatment,the levels of estradiol,progesterone and HCG in the observation group were significantly lower than those in the control group (P<0.01).The disappearance time of abdominal pain and mass,the recovery time of HCG and menstruation in the observation group were significantly shorter than those in the control group (P<0.01).There was no significant difference in the total incidence of adverse reactions between the two groups (13.64% vs 18.18%,P>0.05).Conclusion Xiaozheng Shapei decoction and mifepristone can improve the clinical effect and symptoms of tubal pregnancy.
keywords: Tubal pregnancy Xiaozheng Shapei decoction Mifepristone Qi stagnation and blood stasis syndrome Estradiol Progesterone Human chorionic gonadotropin
文章编号： 中图分类号： 文献标志码：B
基金项目:
| Author Name | Affiliation |
| SUN Wei*,HUANG Song | *Department of Gynecology,Hebei Yanda Hospital,Langfang,Hebei 065201,China |
引用文本：
孙伟,黄松.消癥杀胚方治疗输卵管妊娠气滞血瘀证44例[J].中国临床研究,2020,33(2):237-239.
孙伟,黄松.消癥杀胚方治疗输卵管妊娠气滞血瘀证44例[J].中国临床研究,2020,33(2):237-239.