Abstract:Objective To explore the effects of different rheumatoid factor(RF) levels on cardiac function,complications and quality of life in patients with coronary heart disease(CHD) undergoing percutaneous coronary intervention (PCI). Methods The clinical data of CHD patients receiving PCI from October 2016 to October 2018 were retrospectively analyzed,and 200 patients meeting the inclusion criteria were selected and divided into RF normal group (RF<20 U/ml,n=132),RF high level group (RF≥20 U/ml,n= 68) according to preoperative serum RF levels.The basic data of patients,therapeutic effect and complication rate were observed and compared between two groups. Results There were no significant differences in diabetes,hypertension,hyperlipidemia,smoking rates and gender,height,platelet count,leukocyte count and fibrinogen levels between the groups(all P>0.05),but there were statistical differences in the age,high-sensitivity C-reactive protein level,number and total diameter of stents,degree of coronary lesions and the total length of the stents between two groups(P<0.05,P<0.01).After 1 month of PCI,the left ventricular ejection fraction (LVEF) and quality of life scores significantly increased,and the incidence of postoperative complications significantly decreased in RF normal group compared with RF high level group (P<0.05,P<0.01).The Logistic regression analysis showed that number and total diameter of stents,the degree of coronary lesions were independent infuencing factors of high RF level(all P<0.01). Conclusions In patients with CHD,the level of serum RF is closely related to the degree of coronary lesions,cardiac function,complications and quality of life after PCI.The higher the level of RF,the higher the risk of serious CHD and postoperative complications.