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中国临床研究:2019,32(3):392-394
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康艾注射液对直肠癌腹腔镜手术后胃肠功能恢复及免疫功能的影响
(1.青海省人民医院中央运输部,青海 西宁 810007;2.青海省人民医院检验科,青海 西宁 810007)
Effect of Kang′ai injection on gastrointestinal function recovery and immune function after laparoscopic operation for rectal cancer
摘要
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投稿时间:2018-07-25   网络发布日期:2019-03-22
中文摘要: 目的 探讨康艾注射液对直肠癌腹腔镜手术后胃肠功能恢复及免疫功能的影响。方法 将2017年2月至2018年4月收治的96例直肠癌患者分为研究组和对照组,各48例。对照组采用腹腔镜根治术治疗。研究组在对照组基础上,采用康艾注射液治疗。记录两组的手术情况和胃肠功能恢复情况。检测两组治疗前后CD3+、CD4+、CD4+/CD8+、CD23+的水平。结果 两组的手术时间、术中失血量、清扫淋巴结数、术后镇痛时间差异无统计学意义(P>0.05);观察组的肛门排气时间、肠鸣音恢复时间、术后禁食时间低于对照组,差异有统计学意义(P<0.05);对照组治疗后的CD3+、CD4+、CD4+/CD8+、CD23+明显降低(P<0.05);观察组治疗前后的CD3+、CD4+、CD4+/CD8+、CD23+无明显差异(P>0.05);治疗后,观察组的CD3+、CD4+、CD4+/CD8+、CD23+高于对照组,差异有统计学意义(P<0.05)。结论 康艾注射液能促进直肠癌患者腹腔镜手术后胃肠功能恢复,改善免疫功能。
Abstract:Objective To investigate the Kang′ai injection on gastrointestinal function recovery and immune function after laparoscopic operation for rectal cancer. Methods A total of 96 rectal cancer patients who received treatment from February 2 to April 2018 were selected and divided into study group and control group randomly(n=48, each).The control group was treated with laparoscopic radical resection, and study group was treated with Kang′ai injection on the basis of the control group.The operation situation and gastrointestinal function recovery were recorded.The levels of CD3+, CD4+, CD4+/CD8+, CD23+ were measured before and after treatment in both groups. Results There were no significant differences in operation time, intraoperative bleeding loss, the number of lymph node examined and post-operative analgesia time between two groups (n>0.05).The anal exhaust time, intestinal sounds recovery time and fasting time in the study group were significantly lower than those in the control group.The levels of CD3+, CD4+, CD4+/CD8+, CD23+ was lower in control group after the treatment (P<0.05), but there was no significant difference in observation group.After the treatment, the level of CD3+, CD4+, CD4+/CD8+, CD23+ was significantly higher than that in control group (P<0.05). Conclusion Kang′ai injection could promote the recovery of gastrointestinal function and improve immune function in patients with rectal cancer after laparoscopic surgery.
文章编号:     中图分类号:R 735.3+7    文献标志码:B
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引用文本:
贾珍,罗梦琳.康艾注射液对直肠癌腹腔镜手术后胃肠功能恢复及免疫功能的影响[J].中国临床研究,2019,32(3):392-394.

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